Sudden collapses in the heat in patients on angiotensin type 2 receptor blockers
Citation: Radford PJ. Sudden collapses in the heat in patients on angiotensin type 2 receptor blockers. Rural and Remote Health (Internet) 2014; 14: 2578. Available: http://www.rrh.org.au/articles/subviewnew.asp?ArticleID=2578 (Accessed 21 October 2017)
Context: A clinical case report is presented of some patients taking angiotensin type 2 receptor blockers (AT2RB) who collapsed without warning whilst being active outdoors in the heat.Key words: angiotensin type 2 receptor blockers, hot weather, hypotension, peripheral vasodilation, sudden collapse.
Issues: It is not possible to recognise hypotension due to the heat by testing in a controlled environment such as a doctor’s office. Many people taking AT2RBs may be thus misdiagnosed and inappropriately treated.
Lessons learned: Sudden collapse in a patient on AT2RB who is active in the heat should alert the physician to the possible cause of extreme sensitivity to low-grade volume depletion.
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