Participatory approaches to health often link capacity building as an indispensable process for strengthening the social capital of communities, in order to develop empowerment processes that lead to social transformation at the local level. In Pueblo Rico (Colombia), a capacity building program in cutaneous leishmaniasis and social skills for community work with school students, health workers and local leaders, was implemented from the perspective of social appropriation of knowledge, social innovation in health, and meaningful learning. This article seeks to evaluate the implementation of that pedagogical model, the results of the learning process and the impact of a Capacity Building Program in CL conducted in the municipality of Pueblo Rico.